Treatment of scleroderma heart by D-penicillamine.
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چکیده
منابع مشابه
Treatment of scleroderma heart by D-penicillamine.
A case of severe diffuse systemic sclerosis with cardiomegaly and cardiac failure is described. Treatment with D-penicillamine caused a pronounced decrease in heart size, together with clinical improvement. The use of penicillamine in scleroderma heart has not previously been reported.
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Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whether D-penicillamine treatment was the sole cause of polymyositis or acted as a...
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Serum copper and zinc concentrations and 24 hour urinary copper and zinc excretion were determined serially from the beginning of treatment with D-penicillamine in four children with Wilson's disease. The data show a progressive decrease in both serum copper and zinc concentrations in all. Urinary copper excretion gradually levelled off to approximately 50% of initial values, but zinc excretion...
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Purpose: The aim of this study was to assess the efficacy of D-Penicillamine in reducing lead induced morphometric changes in rat testis. Materials and Methods: Male adult rats were exposed to 0.4% lead acetate in drinking water for 8 weeks. After this period, 6 rats sacrificed and testes were removed to evaluate the effects of lead intoxication. The remained lead exposed rats were divided int...
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ژورنال
عنوان ژورنال: Heart
سال: 1976
ISSN: 1355-6037
DOI: 10.1136/hrt.38.8.864